Episode 1
Mannix has side action on a kidnap case.
Episode 2
Mannix is hired to find out any dirt on Govenor-elect Adam Pierson, and that's when the trouble starts: with his syndicate connections, people are dying fast.
Episode 3
Mannix is set up for the murder of an old girlfriend's husband.
Episode 4
A scientist goes missing with a new formula.
Episode 5
Mannix takes the case of a death row inmate.
Episode 6
A threatened suicide.
Episode 7
An incommunicado coed and a murdered basketball player.
Episode 8
Mannix is hired to vet a prospective bridegroom.
Episode 9
Investigating an insurance claim, Mannix finds himself intensely scrutinized.
Episode 10
A missing boy and a cover-up.
Episode 11
Blackmail in the film industry.
Episode 12
A libel suit against a newspaper at the state capital involves politics and the mob.
Episode 13
An undercover cop's murder exposes a vice operation.
Episode 14
Undercover at a health farm for boozehounds.
Episode 15
Mannix checks out an actress with an enemy.
Episode 16
A psychopath's next victim might be his wife.
Episode 17
The strong friendship between Lew Wickersham and Mannix melts into a violent and deathly feud. The bitter battle begins when Mannix launches an investigation into the theft of a highly secret formula for the development of a laser ray. Stolen plans and sabotage involve Intertect and their agents.
Episode 18
The two paths of the case meet at the water's edge.
Episode 19
Mannix quits rather than chase a necklace and a mobster, and stumbles into a case of murder and fraud.
Episode 20
A missing million leads Mannix out of Intertect as bait for a drug ring.
Episode 21
A faith healer gets blackmailed.
Episode 22
Old labor woes come to light after an attempted murder.
Episode 23
An unsolved murder and an author with enemies.
Episode 24
A fake Renoir is suspected, and the model is in danger.
