Episode 1
A deaf and blind cat stops using its litter box and becomes hostile toward its owners and a new kitten; a couple puts their family plans on hold due to violent feuding between their dog and cat.
Episode 2
A woman and her two feuding cats move to a tiny studio apartment; a ferocious feline attacks a 95-year-old woman.
Episode 3
Bloodthirsty fights lead to urination and frustration; a couple are confused by their pet's odd relationship with a stuffed animal.
Episode 4
A stray cat with a violent side manages to pull on a woman's heartstrings; a cat attacks other felines.
Episode 5
Cat bully Buddy makes life miserable for fellow feline Lita; a kitty named Princess Puffy Pants urinates on everything.
Episode 6
A one-eyed cat with cerebellar hypoplasia torments another feline; a woman's cat urinates on anything and everything.
Episode 7
A cat marks everything in its owner's home; a new cat causes trouble for a couple and their older feline.
Episode 8
An aggressive cat worries an expectant couple; a woman who wants to become an animal behaviorist struggles with two fighting felines of her own.
Episode 9
A woman and her sweet cat are terrorized by a nasty feline; a Persian pooh-poohs the use of a litter box.
Episode 10
A cat-show contestant takes her aggression out on the judges; a man with Crohn's disease cannot stand his cat's constant meowing.
Episode 11
A couple want to move in together, but an uncooperative cat stands in the way of their plans; a demonic feline creates stress for a married couple.
Episode 12
A hellish feline destroys an Italian family's close-knit bonds; a woman moves in with a friend, not knowing that she owns a psychotic cat.
Episode 13
Rick's cat, Buddha, bullies his friend and roommate, Hector; a couple is kept sleeping apart by their cat, Dylan.
Episode 14
A man invites his girlfriend and her foul-tempered feline into his home; two cats that refuse to use a litter box threaten to doom a couple's five-year relationship.
Episode 15
A long friendship between three women is put at risk by the evil behavior of one's cat; a bad Bengal cat threatens to get her owner kicked out of her parents' home.
Episode 16
A shelter cat dubbed "Crazy Daisy" flies into rages and suffers from self-inflicted wounds; she-devil Gizmo's violent ways cause stress for a married couple who want to start a family.
Episode 17
Jackson revisits clients from the first four seasons of the show to see how they and their cats are doing, and also checks back on one of his toughest cases.