Episode 1
The Matsuno brothers try to adapt their show to contemporary times, with mixed results.
Episode 2
The Matsuno brothers struggle to find employment. Later, Osomatsu tries to take an interest in his brothers' lives but winds up being a nuisance to them.
Episode 3
This week's episode is the tidbits collection. Everything from Dekapan-man, to what happens if you try to horde your pachinko winnings, to a bath house quiz.
Episode 4
The Matsuno brothers compete to ensure their divorcing parents will care of each of them. Meanwhile, Totoko asks the brothers for help in a crisis.
Episode 5
Karamatsu gets kidnapped, but his brothers don't do anything. Later, a cat gets to speak and read minds, which causes mayhem for the Matsuno brothers.
Episode 6
The Matsunos are invited to Hatobou's birthday part. Meanwhile, Iyami discovers that his buckteeth contain a rare metal.
Episode 7
Todomatsu starts to work at a stylish cafe. His brothers try to disturb his fulfilling life. / Dekapan and Dayon enjoy a carefree travel together toward north.
Episode 8
Captain Choromatsu waits a man while he carries out a murder case investigation with Detective Todomatsu. / Totoko wants to be a popular idol, but reality is so cruel.
Episode 9
Karamatsu ends up as Chibita's apprentice at his oden stand. Meanwhile, Jyushimatsu falls in love and his brothers try to help him achieve his romance.
Episode 10
Iyami and Chibita dress up as girls, and trick the Matsuno brothers into falling in love with them. It's only a matter of time before this plan goes bad.
Episode 11
A series of Christmas-themed skits. Ichimatsu takes on the role of a Black Santa interrupting a romantic couple's date, while Karamatsu finds himself on a date with an unfortunate ending.
Episode 12
Osomatsu and Totoko host an end of year special broadcast, looking back on previous episodes to determine which of the brothers is the biggest loser.
Episode 13
A salaryman named Sanematsu takes care of his six siblings, the Matsuno brothers become girls and argue, and a fight between Choromatsu and Osomatsu occurs.
Episode 14
The brothers all catch colds. Later, the brothers question Todomatsu about all the things he hasn't told them about his personal life. Choromatsu is a paranoid vice-principal overly worried about plans for his school's cultural festival.
Episode 15
Jyushimatsu goes to a job interview, proving to be a total nuisance for the interviewers. Chibita is asked out on a date by the fairy of a flower he saved.
Episode 16
In an apocalyptic world, the Idol Matsunos battle against Iyami and Dekapan, who are robbing the dry-skinned citizens of all of their lotion. Ichimatsu is forced to pretend to be Karamatsu after Osomatsu catches him wearing his clothes.
Episode 17
Jyushimatsu carries out incredible feats. Meanwhile, the other brothers try to find out when Jyushimatsu developed his odd personality.
Episode 18
Wanting to become the main protagonist of the franchise again, Iyami holds a bizarre kart race to determine who the protagonist of Osomatsu-san will be.
Episode 19
A series of skits take place, set during the Sengoku era. Back in the present, Choromatsu decides to quit being an idol and pursue a job.
Episode 20
Hatabou starts his own catering service. Later, Osomatsu and Karamatsu play as delinquent high school students competing to see who's the toughest. Afterwards, Iyami starts a comedy class hoping to earn a quick buck.
Episode 21
On a rainy evening, the brothers play a game of mahjong. Later, the brothers suddenly find themselves joined by a seventh brother, Godmatsu, who was allegedly born from the goodness that fell out of the brothers' hearts.
Episode 22
Todomatsu holds auditions to take one of his brothers with him to a mixer, struggling to find anyone worth taking. Meanwhile, Iyami meets a kung-fu master who believes him to possess a special technique.
Episode 23
When the family heater runs out of kerosene, the brothers to force each other to get a refill. Meanwhile, Osomatsu, Karamatsu, and Choromatsu find themselves in an underground village populated by a tribe of Dayon people.
Episode 24
Totoko is jealous when people start getting more success than her. Meanwhile, Choromatsu manages to land a job and moves out of the house, with the other brothers soon following suit, leaving just Osomatsu alone.
Episode 25
The brothers quickly abandon their new lifestyles upon learning they have been invited to a baseball tournament for the finale.
