Episode 1
Tim has a massive growth on his back that affects his ability to work and socialize. Daniel has debilitating psoriasis that covers 90% of his body. Gloriana and Yolanda are a mother/daughter duo who have bonded over their bumps.
Episode 2
Traci's confidence has been destroyed after years of bullying from the bumps on her face; Ravon has a unique dangling growth on his leg; David has a large lump.
Episode 3
David is back to see Dr. Lee after she spotted a suspicious growth under his eye. Nicole is depressed because of the bumps all over her neck. Steve has a noticeable lump on his forehead. Allen has a growth on his bicep but is terrified of doctors.
Episode 4
Inoke has a huge, possibly life-threatening bulge on his shoulder; Delano returns with his back lump after Dr. Lee removed a liter of fluid from it; Reed has hundreds of bumps on his chest that burst and leave nasty scars.
Episode 5
Tony has large growths on his nose that impair his breathing. Kevin has a bump in his jawline that is a "lady deterrent." Marie has an unsightly lump on her forehead that makes her a hermit. Tommy's leg bump makes it difficult for him to work.
Episode 6
Gerard is lumpy, he has nearly a hundred lumps varying in size that coat his entire body. Gina has bloody lesions all over and nobody has been able to help her. Eric has a large bump on his head that he calls his "on/off button."